Iran has fired waves of missiles back in return Friday and early Saturday, some of which were not intercepted and struck in Israel. And Israel has since launched new waves of attacks, with the Israel Defense Forces writing “Israel Has Established Aerial Superiority from Western Iran to Tehran” on social media Saturday morning.

Iran’s ambassador to the United Nations said 78 people were killed and more than 320 wounded in the attacks. The Iranian counterattacks killed at least three people in Israel and wounded around 70, according to Israeli health authorities.

The escalation between the two longtime regional rivals has thrown into question President Donald Trump’s quest to strike a new nuclear deal with Iran. Oman Foreign Minister Badr Albusaidi wrote on X Saturday morning that talks originally scheduled for Sunday between the U.S. and Israel in Oman will no longer go forward.

Following the attack, Trump repeatedly praised Israel, America’s longtime ally in the region, embracing the nation’s “successful” attack on Iran’s nuclear program and warning that Iran needs to cut a deal now before it is too late.

“Two months ago I gave Iran a 60 day ultimatum to ‘make a deal,’” he posted on Truth Social early Friday. “They should have done it! Today is day 61. I told them what to do, but they just couldn’t get there. Now they have, perhaps, a second chance!”

But Iran’s top diplomat said the strikes may make a deal less likely, with Foreign Minister Abbas Araghchi calling the continuation of talks “unjustifiable” and saying the U.S. was responsible in a phone call with European diplomats reported on by the state-run news agency IRNA.

“The Iran US talks scheduled to be held in Muscat this Sunday will not now take place,” Albusaidi, Oman’s top diplomat wrote, stressing that “diplomacy and dialogue remain the only pathway to lasting peace.”

The U.S. has denied having any direct involvement with the attacks shortly after they began. But Trump said repeatedly that he was aware they would happen, and praised Israel’s use of American military equipment to carry it out.

The U.S. is also “using its air defenses in the region” to assist Israel in engaging Iranian missiles, POLITICO previously reported.

Israeli Minister Benjamin Netanyahu said in a speech Friday — directed to the Iranian people — that strikes would continue, calling on the populace to resist the Iranian regime. And Khamenei — Iran’s supreme leader — has already started naming replacements for the military officials killed, vowing retribution on Israel in a televised speech Friday.

International leaders have called for both Israel and Iran to cease hostilities, which neither country seems interested in heeding.

French President Emmanuel Macron said Saturday that he spoke with Iranian President Masoud Pezeshkian, saying that French interests and citizens must “not be targeted under any circumstances.”

“I also urged for the utmost restraint to avoid escalation,” he said. “I therefore invited President Pezeshkian to return swiftly to the negotiating table to reach an agreement — the only viable path to deescalation.” Macron’s office said he has also spoke with other world leaders, including Trump.

British Prime Minister Keir Stamer told reporters on his plane — which was en route to G7 meetings — that the U.K. was moving “military assets” to the region.

“We are moving assets, we’ve already been moving assets to the region, including jets, and that is for contingency support across the region,” he said. “Our constant message is deescalate, and therefore everything we’re doing, all discussions we’re having, are to do with deescalation.”

The Associated Press, Ben Johansen, Stefan Boscia and Joshua Berlinger contributed to this report.